So, the controversy surrounding the benefits of supplements or drugs containing l-Cys is still open, mainly regarding their use for some specific treatments
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Their conclusion: sleep improvement under DSIP treatment is of little clinical significance. [11] Bes and colleagues in Amsterdam ran a double-blind matched-pairs parallel-groups design in 16 chronic insomniacs and found the statistically significant effects were weak and in part could be due to an incidental change in the placebo group, with subjective sleep quality unchanged
10.1089/jmf.2016.0063 102 VatsyayanR.ChaudharyP.SharmaA.SharmaR.Rao LelsaniP
Or the Phase 2b result may have been partially driven by chance variation in a relatively small sample